Clinical trial · Observational
Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer is a well known risk factor for venous thromboembolism (VTE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE). Today we know that patients with adenocarcinomas of the gastro intestinal tract (GI-tract) often is in a hypercoagulable state. In our observational study we collect patients admitted to department with a tentative diagnosis of upper GI cancer including pancreas cancer and offer them flow doppler ultrasounds of both legs for diagnosis of DVT in the entire treatment time. The routine CT-scan of the chest is modified to diagnose PE. This will be compared with blood samples analysed for coagulation markers including D-dimer - a fibrinogen degradation product.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Deep Venous Thrombosis | — | UNRESOLVED | — |
| Esophagus Cancer | — | UNRESOLVED | — |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Pancreas Cancer | Pancreatic Carcinoma | ALIAS | 0.90 |
| Pulmonary Embolism | — | UNRESOLVED | — |
| Thrombosis | — | UNRESOLVED | — |
| Venous Thromboembolism | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (3)
- label
- operation
- description
- Patients with upper gastro intestinal cancer who underwent surgery
- label
- palliation
- description
- Patients with upper gastro intestinal cancer who did not underwent surgery
- label
- control
- description
- Persons with no cancer who accepted to be control with blood samples and flow doppler ultrasound examination of both legs.
Primary outcomes (0)
[]Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of upper gastro intestinal cancer. Exclusion Criteria: * Earlier (within prev. 3 years) or concomitant cancer disease of any origin. * Known immunological connective tissue disease. * Mental disorder. * Treatment with heparin, low molecular weight heparin or K-vitamin antagonist at the time of inclusion. * Consent not attained.
References
Publications (0)
Data not yet available