Clinical trial · Interventional
The Physical Exercise and Prostate Cancer Study
Physical Exercise for Patients With Prostate Cancer During Androgen Deprivation Therapy - A Randomized Trial
NCT00658229CI-TRIAL-00008269PEPCcompletedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine the effectiveness of a four months strength training program on physical and psychological health in patients with prostate cancer during androgen deprivation therapy. It is hypothesized a beneficial effect of the intervention on physical and psychological health in patients with prostate cancer treated with androgen deprivation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Strength training group | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Strength training group
- description
- A four months strength training program during androgen deprivation therapy for prostate cancer patietns.
- interventionNames
- Behavioral: Strength training group
- type
- NO_INTERVENTION
- label
- Control group
- description
- Patients in the control group are not discouraged from performing normal activities. They are however asked not to start a strength training program or increase their activity level in the same period as the experimental group is performing their strength training program. We will offer the control group a modified strength training program after the post-intervention assessment.
Primary outcomes (1)
- measure
- lean body mass
- timeFrame
- before ADT, before and after the intervention
Eligibility
Eligibility (as posted)
- Sex
- Male
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Newly diagnosed locally advanced prostate cancer (clinical stage T2 and T3) * Referred to RH and UUS for radiotherapy * \< 75 years * Capable of reading and writing Norwegian * Treating oncologist must approve of the subjects' participation * Living within approximately 1 hour from Oslo by car or public transportation Exclusion Criteria: * Routinely resistance training with manuals * Medication for osteoporosis (i.e. bisphosphonates) * Conditions of a severity that contraindicate exercise without adjusted actions * Mentally incompetent conditions * Conditions of a severity that complicates the ability to participate in a supervised training program
References
Publications (1)
- DERIVEDThorsen L, Nilsen TS, Raastad T, Courneya KS, Skovlund E, Fossa SD. A randomized controlled trial on the effectiveness of strength training on clinical and muscle cellular outcomes in patients with prostate cancer during androgen deprivation therapy: rationale and design. BMC Cancer. 2012 Mar 29;12:123. doi: 10.1186/1471-2407-12-123. PMID 22458865