Clinical trial · Interventional
Yunzhi as Dietary Supplement in Breast Cancer
A Randomized, Parallel, Double-blind, Placebo-controlled, Pilot Clinical Study on the Effects of Yunzhi as Dietary Supplement in 60 Adult Patients Undergoing Adjuvant/Neoadjuvant Chemotherapy for Breast Cancer.
NCT00647075CI-TRIAL-00004195YUNZHI-BCunknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess the effects of a dietary supplement, the traditional Asian mushroom Yunzhi, as adjuvant in the treatment of patients with breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Placebo | Dietary Supplement | — | UNRESOLVED |
| Yunzhi extract | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1
- description
- Yunzhi extract 3.5 g/day
- interventionNames
- Dietary Supplement: Yunzhi extract
- type
- PLACEBO_COMPARATOR
- label
- 2
- description
- Placebo
- interventionNames
- Dietary Supplement: Placebo
Primary outcomes (1)
- measure
- Mean change in signs and symptoms from baseline measured by Visual Analogue Scale (VAS)
- timeFrame
- 6 months
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Women with diagnosis of breast cancer 2. Undergoing adjuvant/neoadjuvant chemotherapy with either FEC, FAC, TAC, or EC + docetaxel combinations. 3. ≥ 18 years of age 4. Performance status: 0-2 5. Ability to provide written informed consent Exclusion Criteria: 1. Any prior history of yunzhi use 2. Use of other herbal remedies during the study duration 3. Significant cardiac, pulmonary, renal, hepatic, gastrointestinal, CNS, psychiatric disease or illicit substance use/abuse that in the opinion of the investigator would make the participant a poor candidate for study participation 4. Pregnancy (for women of childbearing potential, a negative pregnancy test, urine or serum, is required within 14 days prior to randomization) 5. Systemic use of progestins, androgens or other steroids (dexamethasone is allowed if used as antiemetic therapy)
References
Publications (0)
Data not yet available
No reference posted for this study.