Clinical trial · Observational
Ovarian Laser Treatment in Women With Polycystic Ovarian Syndrome: A Randomized Study on the Laser Dose
Transvaginal Ultrasound-Guided Ovarian Interstitial Laser Treatment in Anovulatory Women With Polycystic Ovarian Syndrome: A Randomized Prospective Study on the Effect of Laser Dose Used on the Outcome
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
BACKGROUND: A new effective way, transvaginal ultrasound-guided ovarian interstitial laser-coagulation treatment, in management of anovulation in patients with polycystic ovary syndrome (PCOS), has been presented in the data published. But, the optimal number of laser coagulation points in the ovarian interstitial to be applied at the procedure is unclear. This clinic trial aims to explore an optimal laser dose for this new protocol. METHODS: Fifty-six PCOS women with clomifene citrate-resistant underwent ultrasound-guided transvaginal ovarian interstitial YAG-laser treatment. By random list table，all subjects were randomly divided into four groups in terms of the number of laser coagulation points made in their ovaries as follows: group A, one coagulation point per ovary; group B, two points; group C, three points; group D, four to five points. The size of each point was about 10 mm in diameter on the ovarian plane monitored by transvaginal ultrasound. Postoperative ovulation rate, pregnancy rate and some biochemical parameters were compared among four groups.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anovulation | — | UNRESOLVED | — |
| Infertility | — | UNRESOLVED | — |
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ovarian interstitial laser treatment | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- A
- description
- 14 cases
- interventionNames
- Procedure: ovarian interstitial laser treatment
- label
- B
- description
- 14 cases
- interventionNames
- Procedure: ovarian interstitial laser treatment
- label
- C
- description
- 14 cases
- interventionNames
- Procedure: ovarian interstitial laser treatment
- label
- D
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 23 Years
- Maximum age
- 34 Years
Show eligibility criteria text
Inclusion Criteria: 1. anovulatory women with clomifene citrate (CC)-resistant polycystic ovary syndrome(PCOS) 2. A normal hysterosalpingography or laparoscopy had to have been recorded 3. infertility Exclusion Criteria: 1. Any contraindications to surgery 2. previous treatment with LOD 3. presence of tubal or male factors for infertility
References
Publications (1)
- DERIVEDZhu W, Chen M, Fu Z, Li X, Qin C, Tang X, Chen X. Repeat transvaginal ultrasound-guided ovarian interstitial laser treatment improved the anovulatory status in women with polycystic ovarian syndrome. Eur J Obstet Gynecol Reprod Biol. 2012 May;162(1):50-4. doi: 10.1016/j.ejogrb.2012.02.008. Epub 2012 Mar 6. PMID 22397748