Clinical trial · Interventional
A Clinical Trial of a Radiation Sensitizer in Radiochemotherapy for Thoracic Esophageal Squamous Carcinoma
A Double-Blind, Placebo-Controlled, Randomized Clinical Trial of Sodium Glycididazole in Concurrent Radiochemotherapy for the Treatment of Thoracic Esophageal Squamous Carcinoma
NCT00642239CI-TRIAL-00001458unknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This multicentered clinical trial is going to find out the radio-sensitization action of sodium glycididazole in radiochemotherapy for esophageal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Carcinoma | Esophageal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| placebo | Drug | — | UNRESOLVED |
| Sodium Glycididazole | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- PLACEBO_COMPARATOR
- label
- 2
- description
- Concurrent radiochemotherapy and placebo
- interventionNames
- Drug: placebo
- type
- EXPERIMENTAL
- label
- 1
- description
- concurrent radiochemotherapy and Sodium Glycididazole
- interventionNames
- Drug: Sodium Glycididazole
Primary outcomes (1)
- measure
- tumour local control rate
- timeFrame
- 6 weeks
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * written informed consent * photographically and histologically proven thoracic esophageal squamous carcinoma * stages 2a-3, and stage 4 with only supraclavicular lymph nodes metastasis defined by AJCC(2002) * radiochemotherapy indication * measurable tumor * adequate hematologic, hepatic and renal function * Karnofsky performance status ≥70 * age more than 18years and less than 70 years Exclusion Criteria: * pregnancy and lactation * significant neurologic disease * severe liver and renal malfunction,and Significant medical illness * previous chemotherapy, radiotherapy or immunotherapy * esophagus hemorrhage and esophagus perforation features
References
Publications (0)
Data not yet available
No reference posted for this study.