Clinical trial · Observational
Nipple Areola Complex Conservation
Subcutaneous Mastectomy With Conservation of the Nipple Areola Complex: Broadening the Indications
NCT00641628CI-TRIAL-00001360completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
96 patients were offered a nipple sparing mastectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| mastectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- 1
- interventionNames
- Procedure: mastectomy
Primary outcomes (2)
- measure
- tumour recurrence
- timeFrame
- 07/2003 - 02/2008
- measure
- % of nipple areola complex conservation
- timeFrame
- 07/2003 - 02/2008
Secondary outcomes (2)
- measure
- cosmetics
- measure
- patient's satisfaction
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * breast cancer Exclusion Criteria: * inflammatory breast cancer * clinical skin or nipple involvement
References
Publications (1)
- DERIVEDPaepke S, Schmid R, Fleckner S, Paepke D, Niemeyer M, Schmalfeldt B, Jacobs VR, Kiechle M. Subcutaneous mastectomy with conservation of the nipple-areola skin: broadening the indications. Ann Surg. 2009 Aug;250(2):288-92. doi: 10.1097/SLA.0b013e3181b0c7d8. PMID 19638905