Clinical trial · Interventional
Lifestyle Intervention for Heart Failure
Take Heart: Exercise & Diet Intervention for Heart Failure in Cancer Survivors
NCT00633633CI-TRIAL-00120087active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this behavioral research study is to learn if education and training about exercise can help to change the lifestyle of cancer survivors with symptoms of heart failure.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Heart Failure | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dietary Counseling | Behavioral | — | UNRESOLVED |
| Exercise Training | Behavioral | — | UNRESOLVED |
| Usual Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Group 1
- description
- Usual Care
- interventionNames
- Other: Usual Care
- type
- EXPERIMENTAL
- label
- Group 2
- description
- Exercise Training + Dietary Counseling
- interventionNames
- Other: Usual Care
- Behavioral: Exercise Training
- Behavioral: Dietary Counseling
Primary outcomes (1)
- measure
- Recruitment/Attendance/Drop-Out Rates
- timeFrame
- 1 Year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. diagnosis of NYHA I, II or III heart failure (as identified by any of the following physical findings of heart failure (jugular venous distension, crackles, edema, S3); pulmonary edema on chest x-ray; BNP \> 100 pg/ml; or at least two of the following symptoms: paroxysmal nocturnal dyspnea, shortness of breath, swelling, fatigue; 2. previous chemotherapy that contributed to the development of heart failure (i.e., heart failure develops or worsens after receiving chemotherapy, with no other obvious explanation); 3. oriented to person, place, and time; 4. living in the Houston area (Harris county or a contiguous county), or planning to stay in the area for at least the next 16 weeks. 5. 18 years of age or older. 6. diagnosis of cancer 7. have completed treatment, or are on long-term adjuvant or maintenance chemotherapy only Exclusion Criteria: 1. remain in NYHA class IV heart failure despite therapy; 2. have health problems or current treatments that would make exercise unsafe, as determined by the cardiologist; 3. cannot provide informed consent;
References
Publications (1)
- DERIVEDTsai E, Mouhayar E, Lenihan D, Song J, Durand JB, Fadol A, Massey M, Harrison C, Basen-Engquist K. Feasibility and Outcomes of an Exercise Intervention for Chemotherapy-Induced Heart Failure. J Cardiopulm Rehabil Prev. 2019 May;39(3):199-203. doi: 10.1097/HCR.0000000000000388. PMID 31022003