Clinical trial · Observational
Hereditary Colorectal and Associated Tumor Registry Study
NCT00633607CI-TRIAL-00031706completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| FAP | — | UNRESOLVED | — |
| Hereditary Diffuse Gastric Cancer | Hereditary Gastric Diffuse Adenocarcinoma | ALIAS | 0.90 |
| Juvenile Polyposis Syndrome | — | UNRESOLVED | — |
| Lynch Syndrome | — | UNRESOLVED | — |
| Peutz-Jeghers Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Research Registry | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Establish a Hereditary Colorectal Tumor Registry to facilitate development and implementation of epidemiological, clinical and cancer control research.
- timeFrame
- 1-N/A (up to 8 years)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Identified gene mutation * Personal history of colorectal cancer diagnosed ≤ 50 * Personal history of cancer with tumor studies suggestive of Lynch syndrome * Personal history of multiple primary tumors associated with a hereditary cancer syndrome (colorectal, uterus, stomach, ovary, small bowel, hepatobiliary tract, transitional cell carcinoma of the renal pelvis/ureter, brain) * Personal history of one of the above cancers and a family history of one or more of the above cancers * Personal or family history of diffuse gastric cancer * From a known genetic predisposition family * Personal history of \> 10 colon adenomas (cumulative over a lifetime) * Personal history of any number of hamartomatous polyps * Personal history of multiple large (\> 1cm) serrated polyps to right of sigmoid Exclusion critera: * Individuals under the age of 8 * Individuals who cannot travel to Pittsburgh for in-person enrollment * Individuals who cannot provide informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.