Clinical trial · Interventional
Exercise Training Among Men With Prostate Cancer
Feasibility of Endurance Exercise Training on Cardiovascular Risk Factors Following Radical Prostatectomy Among Men With Localized Prostate Cancer; A Community-Based Intervention
NCT00620932CI-TRIAL-00012469withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objective is to determine the feasibility and acceptability of a home-based endurance exercise program among men diagnosed with clinically localized prostate cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostatectomy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control Group
- description
- These patients will continue with whatever routine exercise they already engage in.
- type
- EXPERIMENTAL
- label
- Exercise Arm
- description
- These patients will participate in a controlled, supervised exercise program.
- interventionNames
- Behavioral: Exercise
Primary outcomes (1)
- measure
- Cardiorespiratory Fitness will be determined using a incremental treadmill test with 12-lead ECG monitoring.
- timeFrame
- 6 months
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Legal age (\>18 years old) 2. An interval of at least 6 weeks between prior radical prostatectomy and study enrollment 3. Karnofsky performance status of at least 70% at study entry 4. Estimated life expectancy of ≥6 months 5. Ability to read and understand English 6. Attending urologist approval 7. Signed informed consent 8. Willingness to be randomized; and 9. No contraindications to exercise as recommended by the American Thoracic Society Exclusion Criteria: 1. Acute myocardial infarction (6 weeks) 2. Unstable angina 3. Uncontrolled arrhythmias causing symptoms or hemodynamic compromise 4. Syncope 5. Acute endocarditis 6. Acute myocarditis or pericarditis 7. Uncontrolled heart failure 8. Acute pulmonary embolus or pulmonary infarction 9. Thrombosis of lower extremities 10. Suspected dissecting aneurysm 11. Uncontrolled asthma 12. Pulmonary edema 13. Room air desaturation at rest ≤85% 14. Respiratory failure 15. Acute noncardiopulmonary disorder that may affect exercise performance or be aggravated by exercise; and 16. Mental impairment leading to inability to cooperate
References
Publications (1)
- DERIVEDJones LW, Hornsby WE, Freedland SJ, Lane A, West MJ, Moul JW, Ferrandino MN, Allen JD, Kenjale AA, Thomas SM, Herndon JE 2nd, Koontz BF, Chan JM, Khouri MG, Douglas PS, Eves ND. Effects of nonlinear aerobic training on erectile dysfunction and cardiovascular function following radical prostatectomy for clinically localized prostate cancer. Eur Urol. 2014 May;65(5):852-5. doi: 10.1016/j.eururo.2013.11.009. Epub 2013 Nov 22. PMID 24315706