Clinical trial · Interventional
The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome
A Clinical Trial to Measure the Effect of DHA-enriched Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat Content in the Polycystic Ovary Syndrome
NCT00620529CI-TRIAL-00003085fopscompletedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
We hypothesise that fish oils will have a beneficial effect on cardiometabolic parameters in women with PCOS. The purpose of this study therefore is to examine the effects of fish oils on blood pressure, heart rate variability and liver fat content in obese women with the polycystic ovary syndrome.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ocean Nutrition 2050 | Dietary Supplement | — | UNRESOLVED |
| Olive oil capsules | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1
- description
- 20/50 fish oil, 1000mg capsules, Ocean Nutrition 2050,4g/day.
- interventionNames
- Dietary Supplement: Ocean Nutrition 2050
- type
- PLACEBO_COMPARATOR
- label
- 2
- description
- olive oil capsules
- interventionNames
- Dietary Supplement: Olive oil capsules
Primary outcomes (1)
- measure
- 24 hour ambulatory systolic blood pressure
- timeFrame
- week 8 and week 24
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * Overweight/obese women with PCOS as per 1990 NIH criteria (see below) * Non-smokers * Age\>18 years, premenopausal * Acceptable to have/be on treatment for type 2 diabetes mellitus and/or dyslipidaemia * Acceptable to be taking the oral contraceptive pill Exclusion Criteria: * Uncontrolled hypertension (BP\>160/100mmHg) * Known co-morbidities including liver or renal disease * Already taking fish oil supplements * Other intercurrent illness (major surgery, CV event) * Smokers * Alcohol intake \>20g/day * Pregnancy * Any metallic implant (contraindication for MRI).
References
Publications (0)
Data not yet available
No reference posted for this study.