Clinical trial · Interventional
Breast MRI as a Preoperative Tool for DCIS
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Breast MRI is a fairly new technology, but it has been well studied. It is now used routinely in many patients with breast cancer. It has been shown to be useful in detecting areas of cancer that cannot be seen using other types of scans or tests. The purpose of this study is to see how often MRI can find other areas of cancer in women with one area of breast cancer, and to determine how having the MRI test affects their treatment. The purpose is also to study any areas of abnormality seen on your MRI with special methods that allow the images of your breast tissue and the microscopic analysis of your breast tissue to be compared very carefully. The study also aims to follow women who enter the study over a 10-year period to determine how often the breast cancer comes back.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Ductal Carcinoma in Situ | Breast Ductal Carcinoma In Situ | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 1
- description
- Women with core biopsy proven DCIS with or without microinvasion seen for surgical consultation at Memorial Sloan-Kettering Cancer Center and for whom operative intervention is planned.
- interventionNames
- Procedure: MRI
Primary outcomes (1)
- measure
- To prospectively evaluate the value of preoperative breast MRI in women with core biopsy-proven DCIS.
- timeFrame
- conclusion of the study
Secondary outcomes (4)
- measure
- To determine the proportion of all patients in this study in whom breast MRI identifies at least one site of cancer separate from the index lesion.
- timeFrame
- conclusion of the study
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
- Maximum age
- 59 Years
Show eligibility criteria text
Inclusion Criteria: * Age less than 60 at time of consent * Clinical stage is consistent with Stage 0 or Stage I T1mic at presentation * Core biopsy proven DCIS or DCIS with microinvasion (invasion ≤0.1 cm), prior to enrollment * Breast surgery to be performed at MSKCC * Informed consent obtained * Female Exclusion Criteria: * Age 60 or over at time of consent * Patients who are pregnant or nursing * Patients with contraindications to breast conservation * Excisional biopsy of DCIS or DCIS with microinvasion, prior to enrollment * Patients with any contraindications to MRI including pacemaker, tissue expander, other metallic surgical implants, weight over 350 lb., previous gadolinium reaction, metal fragments in eye
References
Publications (0)
Data not yet available