Clinical trial · Interventional
Multifunctional Magnetic Resonance Imaging in Predicting Breast Lesions in Women Undergoing Mastectomy for Breast Cancer
Using Magnetic Resonance Techniques to Improve the Characterisation and Localisation of Breast Cancer. A Pilot Observational Study Testing the Accuracy of Multifunctional Magnetic Resonance Techniques in Predicting the Presence, Distribution and Nature of Breast Lesions in Women With Known Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Diagnostic procedures, such as multifunctional magnetic resonance imaging, may help doctors learn the extent of disease and plan the best treatment. PURPOSE: This clinical trial is studying how well multifunctional magnetic resonance imaging works in predicting breast lesions in women undergoing mastectomy for breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| conventional surgery | Procedure | — | UNRESOLVED |
| gadolinium-chelate | Drug | — | UNRESOLVED |
| magnetic resonance imaging | Procedure | — | UNRESOLVED |
| magnetic resonance spectroscopic imaging | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Sensitivity of magnetic resonance (MR) techniques in detecting histopathologically-identified multifocal and multicentric lesions
Secondary outcomes (3)
- measure
- Closeness of agreement between MR techniques and histopathology in localizing satellite lesions relative to the index tumor
- measure
- Assessment of distribution of satellite lesions in relation to index tumor
- measure
- Correlation between histopathological characteristics and signal changes on multifunctional MR
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Biopsy-confirmed invasive ductal carcinoma of the breast * Unifocal disease as defined by clinical examination, mammography, and ultrasound * Patient must be proceeding to mastectomy * Hormone receptor status unknown * No T4d or multifocal disease (as defined on conventional imaging) * Index tumor ≤ 4 cm in diameter PATIENT CHARACTERISTICS: * Menopausal status not specified * Female * No claustrophobia * No cup size of DD or greater PRIOR CONCURRENT THERAPY: * No prior surgery to ipsilateral breast * No prior neoadjuvant chemotherapy * No prior ferromagnetic implants
References
Publications (0)
Data not yet available