Clinical trial · Interventional
Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research study is being done because patients with a history of chest radiation treatment for Hodgkin's disease have been shown to be at increased risk for developing lung cancer a number of years out from treatment. The risk appears to be further increased among patients with a smoking history. Currently, the practice is to recommend annual low-dose chest CT scans in survivors of Hodgkin's disease who have received prior chest radiation treatment and who have at least a moderate smoking history. In this study, the CT scans will be read and interpreted by the study radiologist, and the results recorded in a consistent manner.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| chest computed tomography scan | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Low-dose Chest CT screening
- description
- Annual low-dose Chest CT screening
- interventionNames
- Procedure: chest computed tomography scan
Primary outcomes (1)
- measure
- To Prospectively Collect Data on Chest CT Screening for Patients at Increase Lung-cancer Risk After Hodgkin's Disease.
- timeFrame
- 3 years
- description
- In this study, patients will under annual low-dose chest CT screening. The total number of lung cancer detected through the screening will be recorded
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 5 years or longer from initial Hodgkin's disease diagnosis * Current age 18 or older * Received mediastinal irradiation and/or alkylating-agent based chemotherapy * Smoking history of 10-pack years or more, or current smoker * Pre-approval from the participant's insurance company for the CT study Exclusion Criteria: * Patients with a history of lung cancer * Currently receiving treatment for another cancer diagnosis * Known diagnosis of any metastatic cancer * Pregnant women
References
Publications (0)
Data not yet available