Clinical trial · Observational
Molecular Markers in Thyroid Cancer
Molecular Markers in the Diagnostic and Prognostic Evaluation of Thyroid Cancer
NCT00598364CI-TRIAL-00016288completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate how common gene mutations are in benign and malignant thyroid lesions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Thyroidectomy or neck dissection
- description
- Patients with thyroid cancer or benign thyroid disease (nodules or goiter) who underwent thyroidectomy and/or neck dissection as standard of care.
Primary outcomes (1)
- measure
- The primary outcome is histologic lesion (benign (Graves, Hashimoto's, follicular adenoma or subtype of malignant lesion).
- timeFrame
- 7 years
Secondary outcomes (1)
- measure
- The main secondary outcome to be measured in malignant lesions includes measures of biologic behavior of malignant lesions including capsular and angiolymphatic invasion, local invasion and lymph node metastases at presentation
- timeFrame
- 7 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
Show eligibility criteria text
Inclusion Criteria: * Age 1 - 100 * Benign or malignant thyroid lesion, other malignancy or no thyroid abnormality * Pathologic specimen available for analysis * Ability to provide informed consent (for prospective study, Part Two) * Age greater than age 18 (for normal controls) Exclusion Criteria: * Patients without adequate data for analysis * Histopathologic or cytopathologic diagnosis of for medullary thyroid carcinoma (not derived from the thyroid follicular epithelium), thyroid lymphoma * Unwilling to participate or unable to provide informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.