Clinical trial · Observational
Research on the Environment and Children's Health: Retinoblastoma
NCT00582049CI-TRIAL-00001563completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the research study is to learn more about the causes of retinoblastoma and to identify possible risk factors in the parents of patients with retinoblastoma. This kind of study is called an epidemiology study and is often done by interviewing people with and without the disease. In the case of a childhood disease, the researchers ask about experiences of the parents and children before the disease developed.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Retinoblastoma | Retinoblastoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- 1
- description
- Cases: retinoblastoma patients
- label
- 2
- description
- Controls: first cousins or other blood relatives of the retinoblastoma patients (relative controls) or friends of the retinoblastoma patients or children of friends of the parents (friend controls).
Primary outcomes (1)
- measure
- demographic and exposure information by telephone interview
- timeFrame
- 5 years 4 months
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Cases will be children with sporadic heritable RBL, i.e., bilateral RBL without a family history of the disorder. * Cases will be diagnosed with retinoblastoma in an approximately 7-year period, beginning January 1, 1998 and continuing until the sample size is reached. * The case family must reside in the continental U.S., Alaska, or Canada. * The case family must have a telephone in the household. * The patient's physician must give permission to contact the parents of the case. * The biologic father or mother of the case must be available and consent to be interviewed. * The father or mother must speak English or Spanish. * Genetic counseling regarding RB1 gene mutation analysis must be done prior to registration onto study. Exclusion Criteria: \- Cases that do not meet the above criteria will be ineligible to participate and excluded from the study.
References
Publications (0)
Data not yet available
No reference posted for this study.