Clinical trial · Interventional
Smoking Cessation Intervention for Thoracic Patients
A Pilot Smoking Cessation Study for Newly Diagnosed Lung Cancer Patients
NCT00580398CI-TRIAL-00035253completedPhase 1 / Phase 2Results postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary aim of the proposed study is to develop and assess the feasibility of delivering a smoking cessation intervention to patients undergoing lung surgery that begins before surgery and continues up to 3 months post-discharge. The secondary aim is to assess smoking cessation rates 3 months following surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Smoking cessation counseling | Behavioral | — | UNRESOLVED |
| varenicline | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control
- description
- Usual care included physician advice to quit smoking.
- type
- EXPERIMENTAL
- label
- Intervention
- description
- Intervention participants were provided with a cognitive-behavioral 12-week program consisting of varenicline (1mg bid, with initial titration up over week 1) and smoking cessation counseling targeted to the issues of thoracic cancer patients. We offered 7 counseling sessions but were flexible in offering additional counseling when needed. Counseling was delivered by a certified Tobacco Treatment Counselor using Motivational Interviewing (MI) techniques.
- interventionNames
- Behavioral: Smoking cessation counseling
- Drug: varenicline
Primary outcomes (1)
- measure
- Determination of the Feasibility of a Cognitive Behavioral Smoking Cessation Intervention.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: A patient is eligible if he/she: 1. Is scheduled for a lung resection surgery with either a lung cancer diagnosis or a potential lung cancer diagnosis 2. Smoked a cigarette in the past 2 weeks 3. Is willing to make a pre-surgical quit attempt Exclusion Criteria: Patients will be excluded from the intervention group if they are: 1. Non-English speaking 2. Determined medically ineligible by their surgeon 3. Suffering from psychosis or dementia 4. Have been taking Varenicline for longer than three weeks 5. Have been taking Bupropion (for smoking cessation purposes) for more than three weeks 6. Is otherwise unable to participate in the intervention.
References
Publications (1)
- RESULTPark ER, Japuntich S, Temel J, Lanuti M, Pandiscio J, Hilgenberg J, Davies D, Dresler C, Rigotti NA. A smoking cessation intervention for thoracic surgery and oncology clinics: a pilot trial. J Thorac Oncol. 2011 Jun;6(6):1059-65. doi: 10.1097/JTO.0b013e318215a4dc. PMID 21512406