Clinical trial · Interventional
The Effects of Walnuts, Walnut-Oil, Almonds and Fish Oils on Glucose Homeostasis in Polycystic Ovary Syndrome
Walnuts, Walnut-Oil, Glucose Homeostasis, PCOS
NCT00579904CI-TRIAL-00027152completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to learn more about the effects of walnuts, walnut-oil, almonds and fish oils on blood sugar and insulin levels in polycystic ovary syndrome (PCOS) patients. The hypothesis is that a diet rich in these foods will improve insulin resistance in women with PCOS.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Insulin Resistance | — | UNRESOLVED | — |
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| almonds | Dietary Supplement | — | UNRESOLVED |
| walnuts | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- walnuts
- description
- Patients will be randomized to receive walnuts
- interventionNames
- Dietary Supplement: walnuts
- type
- ACTIVE_COMPARATOR
- label
- almonds
- description
- Patients will be randomized to receive almonds
- interventionNames
- Dietary Supplement: almonds
Primary outcomes (1)
- measure
- The investigators hope to learn the effects of walnuts, walnut-oil, almonds and fish oils on blood sugar and insulin levels in PCOS patients.
- timeFrame
- 3 years
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of polycystic ovary syndrome * Body mass index (BMI) 22-52 Exclusion Criteria: * Habitual dietary intake of less than 30% fat * Use of oral contraceptives, insulin sensitizers, d-chiro inositol, or any other supplements affecting weight or insulin sensitivity during the preceding two months * Impaired glucose tolerance * Diabetes mellitus * Other system illnesses such as renal, hepatic, gastrointestinal, severe hyperlipidemia and hypertension that require medication * Smoking, alcohol intake (more than 2 drinks/week) * The laboratory values used for exclusion of subjects will be fasting glucose \> 110 mg/dl, glycosylated hemoglobin (HgBA1) \> 6.5%, serum creatinine \> 1.5 mg/dl, ALT or AST \> 2x the upper limit of normal, cholesterol \> 250 mg/dl. The investigators will also exclude subjects with hematocrit \< 30%.
References
Publications (0)
Data not yet available
No reference posted for this study.