Clinical trial · Interventional
Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Port wine stain are a congenital, progressive vascular malformation of human skin. The pulsed dye laser is approved by the Food and Drug Administration for the treatment of choice. However, the degree of port wine stain blanching seen following pulsed dye laser treatment remains variable and unpredictable. If the ultimate standard required is complete lesion blanching, the average success rate is below 10%, even after undergoing numerous pulsed dye laser treatments. Moreover, less than 50% of patients achieve 50% fading of their Port wine stain in response to pulsed dye laser therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Port Wine Stains | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pulsed Dye Laser 577 nm | Other | — | UNRESOLVED |
| Pulsed Dye Laser 595 nm | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Pulsed Dye Laser 577 nm
- description
- Pulsed Dye Laser Treatment 577 nm treatment of Port Wine Stain Birthmarks
- interventionNames
- Other: Pulsed Dye Laser 577 nm
- type
- EXPERIMENTAL
- label
- Pulsed Dye Laser 595 nm
- description
- Pulsed Dye Laser Treatment 595 nm treatment of Port Wine Stain Birthmarks
- interventionNames
- Other: Pulsed Dye Laser 595 nm
Primary outcomes (1)
- measure
- Improvement in blanching for the 577 nm Pulsed Dye Laser therapy in comparison with 595 nm
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 6 Months
Show eligibility criteria text
Inclusion Criteria: * Port Wine Stain suitable for comparison testing * Age \> 6 months of age; minor will be accompanied in the room by parents or guardians during laser treatment * Apparent good health as documented by medical history * Ability to understand and carry out subject instructions Exclusion Criteria: * History of photodermatoses or skin cancer * Any therapy within the previous two months to the proposed Port Wine Stain treatment sites * Inability to understand and carry out instructions
References
Publications (0)
Data not yet available