Prevention of Osteoporosis in Breast Cancer Survivors

Inclusion Criteria:

* read, speak and understand English;
* be female;
* be between the ages of 35 and 75;
* have completed treatment (except tamoxifen) for stage 0, I or II breast cancer (i.e. surgery, chemotherapy, radiation) at least 6 months prior to admission to the study;
* be 1 year postmenopausal (12-months amenorrheic; subjects 55-years or younger with history of hysterectomy without oophorectomy must have it confirmed by two baseline measures of FSH \>40 IU/ml);
* have a BMD T-score of -1.0 SD or lower at one or more sites (spine, hip or forearm); and
* have agreement of their primary care provider for participation in the study.

Exclusion Criteria:

* have a recurrence of their breast cancer;
* currently take hormone replacement therapy, bisphosphonates, calcitonin, raloxifene, calcitriol, or glucocorticosteroids.;
* currently do strength/weight training exercises or high impact exercises (such as running, jumping rope, high impact aerobic dance, martial arts, volleyball, or basketball) two to three times weekly;
* have a body mass index (BMI) equal to or greater than 35;
* have serum calcium, creatinine or TSH (if on thyroid therapy) outside the normal limits;
* have active gastrointestinal problems such as dysphagia, esophageal disease, gastritis, duodenitis, or ulcers;
* have Paget=s disease;
* have renal disease (renal stones or serum creatinine levels greater than the upper normal limits);
* have a recent history of a spinal fracture (within the past 6 months);
* have features of an acute fracture on baseline spinal x-rays;
* have other concomitant conditions that prohibit strength/weight training exercises, calcium, or vitamin D intake.