Clinical trial · Interventional
Endoscopic Cyanoacrylate Obliteration vs. Nadolol Treatment in the Prevention of Gastric Variceal Rebleeding
A Randomized Tril of Endoscopic Cyanoacrylate Obliteration vs. Nadolol
NCT00567216CI-TRIAL-00003521GVO-nadololunknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gastric variceal bleeding has a very high rebleeding rate even after endoscopic variceal injection of cyanoacrylate (GVO) which is considered the first choice of endoscopic treatment. Beta-blocker (BB) is effective to lower portal pressure. We hypothesized combination of GVO and BB can further decrease the rebleeding rate.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Variceal Bleeding | — | UNRESOLVED | — |
| Liver Cirrhosis and Hepatoma. | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nadolol | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- G
- description
- Endoscopic injection of cyanoacrylate alone
- type
- ACTIVE_COMPARATOR
- label
- C
- description
- Combination of GVO and nadolol
- interventionNames
- Drug: Nadolol
Primary outcomes (1)
- measure
- Rebleeding
- timeFrame
- 3 yr
Secondary outcomes (1)
- measure
- Complication Survival
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * clinical diagnosis of liver cirrhosis and/or HCC, endoscopically proven gastric variceal bleeding Exclusion Criteria: * younger than 18 y/o or older than 80 y/o, terminal illness, other major systemic disease or malignancy
References
Publications (0)
Data not yet available
No reference posted for this study.