Clinical trial · Interventional
Management of Incidentally Discovered Pancreatic Cysts
A Prospective Study of the Management of Incidentally Discovered Pancreatic Cysts
NCT00550108CI-TRIAL-00001554terminatedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Inability to enroll subjects.
Summary
Brief summary (as posted)
The purpose of this study is to determine the natural history of pancreatic cysts and to determine if these cysts can be effectively treated with a less invasive therapy (ethanol injection vs periodic imaging) rather than surgical resection
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cyst | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ethanol lavage | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- A
- description
- Observation of pancreatic cysts
- type
- EXPERIMENTAL
- label
- B
- description
- Ethanol lavage of pancreatic cysts
- interventionNames
- Other: Ethanol lavage
Primary outcomes (1)
- measure
- Patients not progressing to operation due to the development of symptoms, growth to a maximum diameter of >3cm, or development of a mural nodule.
- timeFrame
- 3 years
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Cyst between 1-3cm * No evidence of a mural nodule, solid component, or septations in the cyst * For patients with multiple cysts, the largest will be evaluated Exclusion Criteria: * Any imaging or cytology concerning for malignancy * Pancreatic Pseudocyst * Gross Cyst \>3cm as measured on MRCP * Clinically active pancreatitis or serum amylase or lipase \>3x upper limit of normal * Coagulopathy (INR\>1.5, PTT\>100, Platelets\<50K) * Inability to tolerate conscious sedation and endoscopy * Rated ASA IV or greater * Prior EUS and aspiration of the pancreatic cyst * Breast feeding * Pregnancy
References
Publications (1)
- BACKGROUNDFernandez-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg. 2003 Apr;138(4):427-3; discussion 433-4. doi: 10.1001/archsurg.138.4.427. PMID 12686529