Clinical trial · Observational
Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic
Neurocognitive Functioning in Adults With Upper Aerodigestive System Cancers
NCT00533884CI-TRIAL-00026852completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Gathering information about how often problems with neurocognitive functioning occur in patients with newly diagnosed upper aerodigestive tract cancers may help doctors learn more about the disease. PURPOSE: This clinical trial is studying neurocognitive functioning in patients with newly diagnosed upper aerodigestive tract cancers receiving treatment at Henry-Joyce Cancer Clinic.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Delirium | — | UNRESOLVED | — |
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Neurocognitive Impairment | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Assessment of therapy complications | Other | — | UNRESOLVED |
| Neurocognitive assessment | Other | — | UNRESOLVED |
| Quality-of-life assessment | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Treatment
- description
- Patients undergoing treatment for head and neck, lung, and esophagus cancers
- interventionNames
- Other: Assessment of therapy complications
- Other: Neurocognitive assessment
- Other: Quality-of-life assessment
Primary outcomes (4)
- measure
- Domain-Specific Neurocognitive Functioning measuring attention, executive functioning, mental processing speed, verbal memory, language, and visuospatial construction at baseline and 3 months after completion of treatment
- timeFrame
- Baseline and 3 months post-treatment
- measure
- Global neurocognitive functioning as measured by the Mini-Mental State Examination (MMSE)
- timeFrame
- Baseline, at each scheduled treatment visit, and at 3 months post-treatment
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Newly diagnosed solid tumors of the upper aerodigestive system, including cancers of the head and neck, esophagus, or lung * Receiving treatment at the Henry-Joyce Cancer Clinic at the Vanderbilt-Ingram Cancer Center * No known brain metastasis PATIENT CHARACTERISTICS: * Able to hear, speak, and understand English * No prior diagnosis of other cancer except basal cell carcinoma PRIOR CONCURRENT THERAPY: * No treatment plans including prophylactic cranial irradiation
References
Publications (0)
Data not yet available
No reference posted for this study.