Clinical trial · Interventional
Bioresorbable Membrane to Reduce Postoperative Small Bowel Obstruction
Bioresorbable Membrane to Reduce Postoperative Small Bowel Obstruction in Patients With Gastric Cancer. A Randomized Clinical Trial
NCT00529412CI-TRIAL-00000872completedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To assess whether the use of Seprafilm reduces the rate of small bowel obstruction in patients who underwent surgery for gastric cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Seprafilm | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- control
- description
- no Seprafilm
- interventionNames
- Other: Seprafilm
- type
- ACTIVE_COMPARATOR
- label
- Seprafilm
- interventionNames
- Other: Seprafilm
Primary outcomes (1)
- measure
- incidence of small bowel obstruction
- timeFrame
- 3 years, more than 6 months after gastrectomy
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of gastric cancer * Operable Exclusion Criteria: * Withdrew consent * Pregnant * Ascites * Distant metastasis * Liver dysfunction (serum total bilirubin \>2.0 mg/dL) * Renal failure (serum creatinine \>1.5 mg/dL) * A past history of small bowel obstruction.
References
Publications (1)
- DERIVEDHayashi S, Takayama T, Masuda H, Kochi M, Ishii Y, Matsuda M, Yamagata M, Fujii M. Bioresorbable membrane to reduce postoperative small bowel obstruction in patients with gastric cancer: a randomized clinical trial. Ann Surg. 2008 May;247(5):766-70. doi: 10.1097/SLA.0b013e3181656d4e. PMID 18438113