Clinical trial · Interventional
Comparison of Pain Therapeutic Effects After Benign Mastectomy
Clinical Comparison of Postoperative Pain Therapeutic Effects After Benign Mastectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
With the incremental trend of benign breast tumor, the surgical process of mastectomy was proceeded too much every day, especially in the Maternal Health Care Hospital, but whether the investigators can find another way to relieve the postoperative pain after such an operation is still unknown. The investigators hypothesized that the pain from the relatively small surgery may not be significant compared to different treatments, even if no drug was delivered to them. The investigators are enrolling patients who underwent mastectomy from benign breast tumor, and are observing the analgesic effects of different drugs.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mastectomy | — | UNRESOLVED | — |
| Pain, Postoperative | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| NSAID | Drug | — | UNRESOLVED |
| Opioid | Drug | — | UNRESOLVED |
| Saline | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (7)
- type
- PLACEBO_COMPARATOR
- label
- I
- description
- No drug was delivered.
- interventionNames
- Drug: Saline
- type
- ACTIVE_COMPARATOR
- label
- II
- description
- Butorphanol tartrate 1mg was given intravenously.
- interventionNames
- Drug: Opioid
- type
- ACTIVE_COMPARATOR
- label
- III
- description
- Butorphanol tartrate 2 mg was given intravenously.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 64 Years
Show eligibility criteria text
Inclusion Criteria: * Chinese * No cardiac and pulmonary diseases * ASA I-II * No alcohol drinking. Exclusion Criteria: * \<19yrs, and \>65yrs * History of central active drugs administration * Drug abuse * Hypertension * Diabetes * Any other chronic diseases.
References
Publications (1)
- RESULTShen X, Wang F, Xu S, Ma L, Liu Y, Feng S, Wang W, Zhao Q, Li X, Zhao L, Yao X, Qu J, Xie B, Wang H, Yuan H, Cao Y, Sun Y, Wang W, Guo L, Song Z, Wang Z, Guan X. Comparison of the analgesic efficacy of preemptive and preventive tramadol after lumpectomy. Pharmacol Rep. 2008 May-Jun;60(3):415-21. PMID 18622068