Clinical trial · Observational
Thermal Signature of Patients Undergoing Radiation Therapy
Phase I Assessment of Thermal Signature of Patients Undergoing Radiation Therapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study closed early without enrollment.
Summary
Brief summary (as posted)
The goal of this clinical research study is to evaluate whether thermal imaging (recording body temperature) can be used to check the body's response to cancer therapy. Primary Objective: * The primary objective of this study is to establish techniques and methodologies of quantifying thermal signatures and their changes for cancer patients undergoing chemoradiation therapy. Secondary Objective: * The secondary objective is to evaluate correspondence between changes of thermal signature of a normal organ, e.g. lung or esophagus, versus the toxicity of that organ from chemoradiation therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Thermal Imaging | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- With Lung Cancer
- description
- Patients with lung cancer.
- interventionNames
- Procedure: Thermal Imaging
- label
- Healthy Participants
- description
- Healthy participants without cancer.
- interventionNames
- Procedure: Thermal Imaging
Primary outcomes (1)
- measure
- Change in Participant Thermal Signature as determined by Thermal imaging (recording body temperature)
- timeFrame
- Imaging session takes about 10 minutes to complete each time, imaging beginning at baseline and continuing till 12 months post therapy, up to 24 months
- description
- Body temperature at the time of the thermal imaging taken using a commercial infrared camera; thermal imaging sessions several times before the cancer treatment starts, during and after the radiotherapy courses. Using thermal images taken from multiple sessions, both the absolute and relative changes of the temperature distribution will be calculated and analyzed. The location of the regions will be guided by the diagnostic computed tomography (CT) and Positron Emission Positron emission tomography (PET)/CT images for temperatures at multiple angles of body, site of radiation for skin reaction, primary cancer site and critical normal organs.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with lung cancers of any stages. 2. Patients will undergo chemotherapy or radiation therapy. 3. Patients with KPS \> 70, are physically mobile and independent, and are able to stand still straight for more than 10 minutes for imaging purposes. 4. Age \>18 years Exclusion Criteria: 1. Patients who had lung surgery within past 3 months. 2. Patients with breast implant or cardiac implant (pace maker or defibrillator). 3. Patients who had skin diseases (e.g. skin desquamation, dermatitis) or other medical conditions that may interfere with thermal measurement. 4. Pregnant woman 5. Extreme obese patients with body mass index \>=35
References
Publications (0)
Data not yet available