Near Infrared/ Ultrasound Dual Modal Imaging for Breast Cancer Diagnosis

Inclusion Criteria:

* Female
* Non-pregnant (as defined by previous tubal ligation, no menses for last 12 consecutive months, or a negative quantitative serum pregnancy test on the day of the procedure.)
* Age: 18 years or older
* Suspicious lesion (BIRAD 4 or 5) identified by mammography and/or by ultrasound.
* A breast biopsy has been scheduled
* The suspicious lesion size is between 0.5 cm and 2 cm.
* The suspicious lesion depth is less than 3 cm from skin surface.
* The suspicious lesion should be clearly evident by ultrasound imaging

Exclusion Criteria:

* Patient with the biopsy performed to the suspicious lesion in the past 2 months on the same breast will be excluded from the study
* Patient with tattoos overlying the area of the suspicious lesion will be excluded from the study
* Patients with prior breast radiation therapy will be excluded from the study
* Patients with prior breast reduction surgery or breast augmentation surgery to the same breast will be excluded from the study
* Patients with previous surgical biopsy at or near the site of the suspicious lesion will be excluded from the study
* Patients with prior history of breast cancer in the same breast will be excluded from the study
* Patient who does not sign the consent form will be excluded from the study
* Patients that have not completed all studies of mammography and/or clinical ultrasound, P-Scan, Terason ultrasound and biopsy will be excluded from this study.