Clinical trial · Interventional
Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia
In-Hospital Individualized Prescriptive Exercise Intervention for Acute Leukemia Patients Undergoing Chemotherapy
NCT00499759CI-TRIAL-00006381completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: An individualized exercise program may be effective in lessening fatigue and depression and improving quality of life in patients undergoing chemotherapy for leukemia. PURPOSE: This clinical trial is studying how well individualized exercise programs work in patients receiving chemotherapy for newly diagnosed acute or relapsed myeloid leukemia or lymphoblastic leukemia.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Depression | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
| Leukemia | Leukemia | ONTOLOGY_EXACT | 0.90 |
| Musculoskeletal Complications | — | UNRESOLVED | — |
| Psychosocial Effects of Cancer and Its Treatment | — | UNRESOLVED | — |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Body Composition | Behavioral | — | UNRESOLVED |
| Cardiorespiratory assessment | Behavioral | — | UNRESOLVED |
| Dynamic muscular endurance | Behavioral | — | UNRESOLVED |
| Handgrip evaluation | Behavioral | — | UNRESOLVED |
| Resting vitals | Behavioral | — | UNRESOLVED |
| Timed Get-up and Go test (TGUG). | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Effects of an individualized prescriptive exercise intervention
- timeFrame
- 6 weeks
- description
- All patients will participate in an individualized prescriptive exercise intervention 3 to 4 times per week (depending on the physical status of each patient during each week) for a period of 6 weeks. The exercise intervention will begin on week 1 of the study, the day after the first battery of initial assessments is concluded. Each exercise session will be divided into two bouts. One bout will be administered in the morning and the second one late in the afternoon
Secondary outcomes (1)
- measure
- Number of subjects experiencing fatigue, depression, and quality of life issues
- timeFrame
- 6 weeks
- description
- The Functional Assessment of Cancer Therapy-General (FACT-G) will be administered to assess the levels of fatigue, and quality of life on weeks 2, 3 and 5 of the 6 week trial. The Center for Epidemiologic Studies Depression Scale (CES-D) will be also administered to explore the effects of exercise on depression on weeks 2, 3 and 5 of the 6 week trial.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Newly diagnosed acute or relapsed myeloid or lymphoblastic leukemia * Currently receiving re-induction therapy or designated for chemotherapy treatment * Expected hospital stay of 3-4 weeks or longer * Participation in the study must be approved by the physician directly responsible for the patient's care while at University of North Carolina Hospitals PATIENT CHARACTERISTICS: * No condition that would compromise the patient's ability to participate in the exercise rehabilitation program, including any of the following: * Immune deficiency * Acute or chronic bone, joint, or muscular abnormalities * Acute or chronic respiratory disease * Cardiovascular disease PRIOR CONCURRENT THERAPY: * See Disease Characteristics
References
Publications (0)
Data not yet available
No reference posted for this study.