Clinical trial · Interventional
Hatha Yoga in Improving Physical Activity, Inflammation, Fatigue, and Distress in Breast Cancer Survivors
Breast Cancer Survivors: Physical Activity, Inflammation, Fatigue, and Distress
NCT00486525CI-TRIAL-00014411completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Yoga may improve inflammation, fatigue, and depression in female breast cancer survivors. PURPOSE: This randomized clinical trial is studying how well Hatha yoga works in improving physical activity, inflammation, fatigue, and distress in female breast cancer survivors.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Depression | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
| Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Yoga Therapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I: Yoga Therapy
- description
- Patients participate in a Hatha yoga session over 90 minutes twice weekly for 12 weeks. Patients are also encouraged to practice yoga at home using the appropriate DVD/video segments for the month.
- interventionNames
- Procedure: Yoga Therapy
- type
- NO_INTERVENTION
- label
- Arm II: Wait-List
- description
- Wait-listed women were told to continue performing their usual activities, and to refrain from beginning any yoga practice. After their final assessment they were offered the yoga classes.
Primary outcomes (6)
- measure
- Stimulated ln (TNF-a)
- timeFrame
- Immediately post-treatment and 3 months post-treatment
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Stage 0-IIIA breast cancer survivor * Completed cancer treatment within the past 36 months (except for tamoxifen/aromatase inhibitors) * At least 2 months since prior surgery, adjuvant therapy, or radiotherapy, whichever occurred last * Women who are not currently practicing yoga and have not participated in any of the following activities: * Meditation, tai chi, or related activities * Yoga or tai chi within the past 6 months * Had classes for or practiced yoga for more than 3 months * Women who typically engage in a total of 5 or more hours of vigorous physical activity per week are not eligible * No inflammatory breast cancer PATIENT CHARACTERISTICS: Inclusion criteria: * Hemoglobin ≥ 10 g/dL (patients with a hemoglobin of \< 10 g/dL may be retested in 6 weeks after treatment of anemia and allowed to participate in study if blood counts recovered) * Physically able to fully participate in yoga intervention Exclusion criteria: * Inability to comfortably get up and down from the floor 2-3 times in a session * Breathing problems requiring use of oxygen * Problems walking without a cane or walker assistance * Prior knee or hip replacement with limited movement in the joint * Inability to comfortably lie on the stomach * Alcohol, or drug abuse * Diagnosis of any of the following conditions: * Diabetes * Chronic obstructive pulmonary disease * Uncontrolled hypertension * Evidence of liver or kidney failure * Symptomatic ischemic heart disease * Significant visual or auditory problems * Mental disorder or cognitive impairment * Notable serious cardiovascular history (e.g., prior life-threatening abnormal heart rhythms) * Other medical conditions involving the immune system such as autoimmune and/or inflammatory diseases including rheumatoid arthritis and ulcerative colitis * History of breast or any other cancer, except basal or squamous cell skin cancer PRIOR CONCURRENT THERAPY: * See Disease Characteristics * No regular use of medications with major immunological consequences (e.g., steroids)
References
Publications (1)
- RESULTKiecolt-Glaser JK, Bennett JM, Andridge R, Peng J, Shapiro CL, Malarkey WB, Emery CF, Layman R, Mrozek EE, Glaser R. Yoga's impact on inflammation, mood, and fatigue in breast cancer survivors: a randomized controlled trial. J Clin Oncol. 2014 Apr 1;32(10):1040-9. doi: 10.1200/JCO.2013.51.8860. Epub 2014 Jan 27. PMID 24470004