Clinical trial · Interventional
Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients
Preoperative Treatment With NSAID in Colorectal Cancer Patients in Relationship to Tumor Host Reactions
NCT00473980CI-TRIAL-00006639completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study is designed to evaluate effects of NSAIDs on immune activity inside and close to tumor tissue in patients with colorectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Indomethacin, celecoxib, esomeprazole | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Drug
- description
- Treatment with indomethacin or celecoxib
- interventionNames
- Drug: Indomethacin, celecoxib, esomeprazole
- type
- SHAM_COMPARATOR
- label
- SHAM
- description
- Sham treatment
- interventionNames
- Drug: Indomethacin, celecoxib, esomeprazole
Primary outcomes (1)
- measure
- Immune reactivity
- timeFrame
- Acute evaluations
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Colon carcinoma scheduled for curative operation Exclusion Criteria: * Diabetes, steroid medication, liver and kidney impairment
References
Publications (0)
Data not yet available
No reference posted for this study.