Clinical trial · Observational
Aerobic Capacity and Body Composition in Colon Cancer Patients
Changes in Aerobic Capacity and Body Composition in Colon Cancer Patients Receiving Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Recent studies have shown that survival after a colorectal cancer diagnosis may be affected by a person's activity level and body size. This research says that for colorectal cancer patients, the less active and more obese they are, the more likely they are to have a cancer recurrence or die from their cancer. Chemotherapy has been shown to reduce activity levels, fitness, and body size in some cancer patients. However, it is not known how chemotherapy specific for colon cancer patients affects their activity levels, fitness, and body size. The main goal of our study will be to look at how chemotherapy treatments affect the fitness, activity levels, and body size in colon cancer patients. In order to do this, we will measure these variables before chemotherapy treatments, and at 1 and 6 months following the end of treatment. Our results will show how chemotherapy affects fitness, activity levels, and body size in colon cancer patients and provide data to help in designing an exercise intervention specifically for colon cancer survivors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Neoplasms | Colon Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * histologically confirmed colon cancer (Stage III and those Stage II patients deemed high-risk * approval of the treating oncologist * scheduled to received chemotherapy * able to understand and provide written informed consent in English * 18+ years of age * no uncontrolled co-morbidities (including hypertension, cardiac illness, psychiatric condition, etc.) * negative ECG as assessed during maximal graded exercise test Exclusion Criteria: * metastatic or recurrent colon cancer patients * pregnancy * any uncontrolled medical condition that would be a contraindication to exercise (assessed by treating oncologist) * unwilling to attend, travel to or participate in the assessments at all 3 time points In addition, 10 patients meeting all of the eligibility criteria who are not scheduled to receive chemotherapy will also be recruited to the study to serve as "surgery only" controls.
References
Publications (0)
Data not yet available