Clinical trial · Interventional
Nutritional Intervention in Geriatric Oncology
Nutritional Intervention in Geriatric Oncology in Patients at Risk of Undernutrition
NCT00459589CI-TRIAL-00007218INOGADcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Older patients with cancer are poorly treated or not treated at all. A previous study in the south west of France (364 patients) showed that patients receiving chemotherapy had short survival times which strongly depended on nutritional status. In this study, the researchers would like to evaluate if individual dietician follow-up at each cycle of chemotherapy increases survival of patients at risk of undernutrition.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aging | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Undernutrition | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| nutritional intervention with dietician plus usual nutritional care | Behavioral | — | UNRESOLVED |
| usual nutritional care | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1
- description
- nutritional intervention with dietician at each cycle of chemotherapy in 6 first cycles to maintain 30 kcal/kg/d and 1.2 protein/kg/d
- interventionNames
- Behavioral: nutritional intervention with dietician plus usual nutritional care
- type
- ACTIVE_COMPARATOR
- label
- 2
- interventionNames
- Behavioral: usual nutritional care
Primary outcomes (1)
- measure
- Survival
- timeFrame
- 1 year
Secondary outcomes (13)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Over 70 years of age * Histologically proven cancer * Treatment by chemotherapy * Risk of undernutrition according to MNA score between 17 and 23.5 * ECOG ≤ 3 * Life expectancy \> 12 weeks * Patient affiliated with the French social security regimen * Written informed consent Exclusion Criteria: * MNA score under 17 or over 23.5 * Geographic, psychological, or social conditions potentially hampering compliance with the study protocol * Symptomatic central nervous system (CNS) metastases * Chemotherapy treatments not published as standard protocols * Treatment that does not allow geriatric evaluation and dietician follow-up.
References
Publications (1)
- DERIVEDBourdel-Marchasson I, Blanc-Bisson C, Doussau A, Germain C, Blanc JF, Dauba J, Lahmar C, Terrebonne E, Lecaille C, Ceccaldi J, Cany L, Lavau-Denes S, Houede N, Chomy F, Durrieu J, Soubeyran P, Senesse P, Chene G, Fonck M. Nutritional advice in older patients at risk of malnutrition during treatment for chemotherapy: a two-year randomized controlled trial. PLoS One. 2014 Sep 29;9(9):e108687. doi: 10.1371/journal.pone.0108687. eCollection 2014. PMID 25265392