Clinical trial · Interventional
Pilot Study for Evaluation of the Need for Protective Ileostomy After Low Anterior Resection Due to Rectal Cancer
NCT00457327CI-TRIAL-00001515terminatedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): RCT with same hypothesis ended and showed a superiority for protective ileostomy after lower anterior rectum resection.
Summary
Brief summary (as posted)
The purpose of this study is to determine whether protective ileostomy is required after low anterior resection due to rectal cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| protective ileostomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Morbidity and mortality until day 30 postoperative
Secondary outcomes (2)
- measure
- Quality of life
- measure
- Ranking of factors influencing quality of life
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * radical resectable rectal cancer * low sphincter-preserving resection of carcinomas of the lower and middle third * preoperative normal continence * preoperative normal sphincter function * complete rings after stapler anastomosis * impermeability of anastomosis for air * written informed consent Exclusion Criteria: * reduced cooperation or drug abuse * pregnancy * psychosis * age under 18 years
References
Publications (1)
- DERIVEDUlrich AB, Seiler C, Rahbari N, Weitz J, Buchler MW. Diverting stoma after low anterior resection: more arguments in favor. Dis Colon Rectum. 2009 Mar;52(3):412-8. doi: 10.1007/DCR.0b013e318197e1b1. PMID 19333040