Clinical trial · Interventional
AML Treatment in Untreated Adult Patients
AML Treatment in Untreated Adult Patients According to EORTC-GIMEMA Protocols AML8 and AML10
NCT00449319CI-TRIAL-00030396LAM99PunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The present therapy intends to be an homogeneous treatment for AML patients based on a pretreatment with hydroxiurea plus an induction therapy with the standard arm with Daunorubicine as according to EORTC-GIMEMA AML10 study. The post-remissional treatment is based on transplant with HLA compatible donor is foreseen for all patients and autologous transplant for those without HLA compatible donor available.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukemia, Myelocytic, Acute | Leukemia | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Daunorubicine | Drug | Daunorubicin | ALIAS |
| Identification of appropriate therapies according to risks factors | Procedure | — | UNRESOLVED |
| Transplant | Procedure | — | UNRESOLVED |
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 61 Years
Show eligibility criteria text
Inclusion Criteria: * AML "de novo" with bone marrow blasts \<=30% * Performance status: 0-3 * FAB subtype: all except M3 * Written informed consent Exclusion Criteria: * age \<15 years and \>= 61 years * pretreated AML with chemiotherapy (except Idrossiurea) or radiotherapy or corticosteroids for more than 7 days. * diagnosis of acute promyelocitic leukemia (M3) * Performance status = 4 * Uncontrolled infection
References
Publications (0)
Data not yet available
No reference posted for this study.