Clinical trial · Interventional
Selenium and Prostate Cancer: Clinical Trial on Availability to Prostate Tissue and Effects on Gene Expression
NCT00446901CI-TRIAL-00004563SeProscompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to determine whether selenium supplementation leads to changes in selenium levels and gene expression profiles in prostate tissue.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
| Prostatic Neoplasms | Prostate Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Selenium | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- PLACEBO_COMPARATOR
- label
- Placebo
- description
- Placebo
- interventionNames
- Dietary Supplement: Selenium
- type
- EXPERIMENTAL
- label
- Selenium (selenized yeast)
- description
- Selenium (selenized yeast) tablets, 300 ug/day
- interventionNames
- Dietary Supplement: Selenium
Primary outcomes (2)
- measure
- selenium levels in prostate tissue
- timeFrame
- after 5 weeks of intervention with selenium or placebo
Eligibility
Eligibility (as posted)
- Sex
- Male
Show eligibility criteria text
Inclusion Criteria: * male * biopsy proven prostate cancer * scheduled for radical prostatectomy Exclusion Criteria: * liver diseases (e.g. hepatitis) * kidney diseases * inflammatory bowel diseases * use of dietary supplements containing selenium * adjuvant therapy for prostate cancer (e.g. hormonal therapy, HIFU) * previously or concurrent diagnosed with cancer, other than prostate cancer
References
Publications (0)
Data not yet available
No reference posted for this study.