Clinical trial · Observational
Study of Families With Melanoma
Melanoma Family Case-Control Study Protocol
NCT00445783CI-TRIAL-00011703unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: A study that evaluates patients' lifestyle, skin, and blood and tissue samples may help doctors understand the risk factors for melanoma relapse. PURPOSE: This clinical trial is studying the risk factors for melanoma in families with melanoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Melanoma (Skin) | Melanoma | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (7)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| examination | Procedure | — | UNRESOLVED |
| gene expression analysis | Genetic | — | UNRESOLVED |
| immunohistochemistry staining method | Other | — | UNRESOLVED |
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| mutation analysis | Genetic | — | UNRESOLVED |
| mutation carrier screening | Procedure | — | UNRESOLVED |
| study of high risk factors | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- Lifestyle factors governing relapse from melanoma
- measure
- Genes governing relapse from melanoma
- measure
- Sun exposure and genes that cause melanoma
- measure
- Unusual moles related to sun exposure and genes that cause melanoma
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS:
* Meets 1 of the following criteria:
* Newly diagnosed primary invasive melanoma (patient group)
* Lentigo maligna malignant melanoma allowed
* Rare variants of melanoma allowed, including any of the following:
* Acral lentiginous
* Subungual
* Ear, nose, and throat
* Oropharyngeal
* Perineal
* Vaginal
* Vulval
* Rectal
* Nodal with no known primary
* Patients undergoing sentinel node biopsy are eligible
* No in situ melanoma, melanocytic intraepidermal neoplasia, or ocular melanoma
* Healthy participant meeting either of the following criteria (control group):
* Relative of a patient who was diagnosed with melanoma after September 2005
* Healthy volunteer who is age- and sex-matched for patients who were diagnosed with melanoma before October 2005
PATIENT CHARACTERISTICS:
* Not specified
PRIOR CONCURRENT THERAPY:
* Not specifiedReferences
Publications (0)
Data not yet available
No reference posted for this study.