Clinical trial · Observational
Changes in Breast Density and Breast Cancer Risk in Women With Breast Cancer and in Healthy Women
Longitudinal Changes in Mammographic Density and Risk of Breast Cancer
NCT00445445CI-TRIAL-00043315completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying mammograms for breast density changes over time may help doctors predict breast cancer risk. PURPOSE: This natural history study is looking at changes in breast density and gathering health information over time to assess breast cancer risk in women with breast cancer and in healthy women.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| breast imaging study | Procedure | — | UNRESOLVED |
| physiologic testing | Other | — | UNRESOLVED |
| radiomammography | Procedure | — | UNRESOLVED |
| screening questionnaire administration | Other | — | UNRESOLVED |
| study of high risk factors | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Patients
- description
- Histologically confirmed breast cancer that was diagnosed between the years 2002-2004
- interventionNames
- Other: physiologic testing
- Other: screening questionnaire administration
- Procedure: breast imaging study
- Procedure: radiomammography
- Procedure: study of high risk factors
- label
- Healthy participants
- description
- Healthy participant who is receiving routine medical care (e.g., screening mammograms. Healthy participants are frequency-matched by age (± 2 years) and ethnicity.
- interventionNames
- Other: physiologic testing
- Other: screening questionnaire administration
- Procedure: breast imaging study
- Procedure: radiomammography
- Procedure: study of high risk factors
Primary outcomes (3)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Patient at the University Hospitals Breast Center and primary care clinics within the University Hospitals system * Have at least 3 screening mammograms since 1994 * for cases, diagnosis with breast cancer between 2004-2006 Exclusion criteria: * having had irregular screening (less than 3 mammorgrams since 1994) * Having breast implants * Known carriers of BRCA1/BRCA2 genes * Unable to give written consent
References
Publications (0)
Data not yet available
No reference posted for this study.