Clinical trial · Interventional
MRI in Evaluating the Effect of Efaproxiral on the Brain in Patients With Recurrent or Progressive Glioma Enrolled on Clinical Trial NABTT-9806
Effect of RSR13 on T2 and T2* Cranial MRI Images: An Imaging Companion Study to NABTT 9806
NCT00433472CI-TRIAL-00018703withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): not enough interest
Summary
Brief summary (as posted)
RATIONALE: Diagnostic procedures, such as MRI, may help doctors learn how efaproxiral works in the brain and help plan the best treatment. PURPOSE: This clinical trial is using MRI to evaluate the effect of efaproxiral on the brain in patients with recurrent or progressive glioma receiving treatment on clinical trial NABTT-9806.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain and Central Nervous System Tumors | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| magnetic resonance imaging (MRI) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- MRI -
- description
- MRI scan to be complete to look at RSR13 on measurement of T2 and T2\* on MRI Procedure/surgery magnetic resonance imaging (MRI)
- interventionNames
- Device: magnetic resonance imaging (MRI)
Primary outcomes (5)
- measure
- Measurable effect of efaproxiral on the brain as measured by T2 and/or T2* MRI
- measure
- Predicted oxygenation changes based on observed T2 MRI changes
- measure
- Effects of efaproxiral on T2 and T2* MRI relaxation times of normal areas of the brain
- measure
- Baseline oxygen extraction ratios in tumors
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Recurrent or progressive glioma * Currently enrolled on clinical trial NABTT-9806 PATIENT CHARACTERISTICS: * No severe claustrophobia * No cardiac pacemaker * No MRI-incompatible metallic implant PRIOR CONCURRENT THERAPY: * Not specified
References
Publications (0)
Data not yet available
No reference posted for this study.