Clinical trial · Interventional
Ambulatory Physical Exercise Program in Hematopoietic Stem Cell Transplantation Recipients
Physical Exercise to Improve Physical Performance and Health Related Quality of Life in Hematopoietic Stem Cell Transplantation Recipients
NCT00402753CI-TRIAL-00002973completedEarly Phase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The proposed study in an inception cohort of patients with hematological malignancies treated with PBSCT is designed to evaluate the effects of a physical exercise intervention on muscular-skeletal, physical activity and quality of life outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematopoietic Stem Cell Transplantation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ambulatory Physical Exercise Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group 1
- description
- Physical exercise group: Combined supervised physical activity: Endurance and Resistive strength
- interventionNames
- Behavioral: Ambulatory Physical Exercise Program
- type
- NO_INTERVENTION
- label
- Group 2
- description
- Usual care control group
Primary outcomes (6)
- measure
- Musculoskeletal performance
- timeFrame
- Baseline -3 months - 6 months
- measure
- Knee extension strength
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Status after high-dose chemotherapy following Hematopoietic Stem Cell Transplantation * Willing to enter a physical exercise program * Good understanding of the German language * Written informed consent Exclusion Criteria: * Uncontrolled cardiovascular disease and myocardial infarction in the previous six months * Uncontrolled hypertension * Uncontrolled thyroid disease * Uncontrolled diabetes * Diagnosis of depression before entering the study.
References
Publications (3)
- BACKGROUNDKnols R, Aaronson NK, Uebelhart D, Fransen J, Aufdemkampe G. Physical exercise in cancer patients during and after medical treatment: a systematic review of randomized and controlled clinical trials. J Clin Oncol. 2005 Jun 1;23(16):3830-42. doi: 10.1200/JCO.2005.02.148. PMID 15923576
- BACKGROUNDSchmitz KH, Holtzman J, Courneya KS, Masse LC, Duval S, Kane R. Controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1588-95. doi: 10.1158/1055-9965.EPI-04-0703. PMID 16030088
- BACKGROUNDGalvao DA, Newton RU. Review of exercise intervention studies in cancer patients. J Clin Oncol. 2005 Feb 1;23(4):899-909. doi: 10.1200/JCO.2005.06.085. PMID 15681536