Clinical trial · Interventional
Bangladesh Vitamin E and Selenium Trial
NCT00392561CI-TRIAL-00065965BESTcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate whether selenium and/or vitamin E are effective in preventing non-melanoma skin cancers.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non-melanoma Skin Cancer | Skin Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Selenium | Dietary Supplement | — | UNRESOLVED |
| vitamin E | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- 1
- description
- Selenium
- interventionNames
- Dietary Supplement: Selenium
- type
- EXPERIMENTAL
- label
- 2
- description
- Vitamin E
- interventionNames
- Dietary Supplement: vitamin E
- type
- EXPERIMENTAL
- label
- 3
- description
- Vitamin E + Selenium
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Manifest arsenic skin lesions (melanosis, leucomelanosis, or keratosis) * Aged 25 to 65 years * Permanent resident of study area Exclusion Criteria: * Pregnancy * Clinically too ill (enlarged spleen or liver) * Presence of gangrene * Cancer
References
Publications (1)
- DERIVEDJasmine F, Almazan A, Khamkevych Y, Argos M, Shahriar M, Islam T, Shea CR, Ahsan H, Kibriya MG. Gene-Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy. Cells. 2025 Jan 10;14(2):95. doi: 10.3390/cells14020095. PMID 39851523