Clinical trial · Interventional
Use of Cone Beam Kilovoltage Imaging in Patients Receiving Radiation Therapy for Head and Neck Cancer
Evaluation of Cone Beam Kilovoltage Imaging During Radiation Therapy for Tumors of the Head and Neck
NCT00358007CI-TRIAL-00089294terminatedPhase 2Results postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Administratively Terminated by PI
Summary
Brief summary (as posted)
To evaluate the use of cone beam computed tomography in treating head and neck to hopefully reduce side effects
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Neoplasms | Head and Neck Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PTV Reduction | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Cone Beam CT
- interventionNames
- Device: PTV Reduction
Primary outcomes (2)
- measure
- Average Interfraction Shift of Patients Undergoing Radiotherapy
- timeFrame
- Daily prior to radiation
- description
- Determine the magnitude of the systematic error of patient positioning as determined by cone beam CT (CBCT) and the desired placement based on the treatment planning CT scan. Every day, prior to radiation treatment, a CBCT will be performed. The CBCT images will be compared to the radiation therapy planning CT image just taken.
- measure
- Average Residual Error Motion of Patients Undergoing Radiotherapy
- timeFrame
- Daily after each radiotherapy treatment
- description
- To determine the magnitude of random variance (random error) in radiotherapy treatment of head and neck neoplasms
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * any patient receiving radiation therapy for a head and neck tumor assigned to the new Elekta Synergy Linare Accelerator Exclusion Criteria: * NA
References
Publications (1)
- RESULTDen RB, Doemer A, Kubicek G, Bednarz G, Galvin JM, Keane WM, Xiao Y, Machtay M. Daily image guidance with cone-beam computed tomography for head-and-neck cancer intensity-modulated radiotherapy: a prospective study. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1353-9. doi: 10.1016/j.ijrobp.2009.03.059. Epub 2009 Jun 18. PMID 19540071