Clinical trial · Observational
Myoma Microvascularization Analysis Using Sonovue Before and After Uterine Artery Embolization
NCT00351494CI-TRIAL-00000993unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Contrast-enhanced ultrasound is supposed to improve the detection of myomas as well as improve the follow-up after specific treatments like embolization. It will also help the investigators better understand the mechanism of success or failure for embolization and could reduce the amount of particles injected by determining the endpoint of the procedure in order to treat the myomas while preserving the myometrium.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myoma | Myoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| contrast enhanced ultrasonography | Procedure | — | UNRESOLVED |
| embolization | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To investigate the usefulness of contrast-enhanced ultrasound with real-time imaging technique in the assessment of vascular patterns from myomas myometrium and ovaries before and after uterine artery embolization
- timeFrame
- Inclusion period and follow-up
Secondary outcomes (3)
- measure
- Accordance between contrast-enhanced imaging and IRM
- timeFrame
- inclusion period and follow-up
- measure
- Accordance between early vascular patterns due to embolization of the fibroma and the success of the technique which is evaluated after 6 month
- timeFrame
- inclusion period and follow-up
- measure
- Relationship between the post embolization pain and the vascular change of the fibroma and the myometrium
- timeFrame
- inclusion period
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Uterine myomas with solid tissue (greater diameter lower than 15 cm) * The embolization is planified during the 15 days after the contrast ultrasonography * Written informed consent is signed Exclusion Criteria: * Intracavitary uterine mass possibly due to a polyp or endometrial cancer * Necessity of using the endovaginal way of ultrasonography because of the myoma's size and accessibility * Menopause * Pregnancy and breastfeeding * Recent cardiac affection * History of acute cardiac disease
References
Publications (3)
- BACKGROUNDTranquart F, Brunereau L, Cottier JP, Marret H, Gallas S, Lebrun JL, Body G, Herbreteau D, Pourcelot L. Prospective sonographic assessment of uterine artery embolization for the treatment of fibroids. Ultrasound Obstet Gynecol. 2002 Jan;19(1):81-7. doi: 10.1046/j.0960-7692.2001.00535.x. PMID 11851974
- BACKGROUNDMarret H, Cottier JP, Alonso AM, Giraudeau B, Body G, Herbreteau D. Predictive factors for fibroids recurrence after uterine artery embolisation. BJOG. 2005 Apr;112(4):461-5. doi: 10.1111/j.1471-0528.2004.00487.x. PMID 15777445
- BACKGROUNDMarret H, Tranquart F, Sauget S, Alonso AM, Cottier JP, Herbreteau D. Contrast-enhanced sonography during uterine artery embolization for the treatment of leiomyomas. Ultrasound Obstet Gynecol. 2004 Jan;23(1):77-9. doi: 10.1002/uog.944. PMID 14971005