Clinical trial · Observational
Osteoporosis in Children With ALL
Incidence of Osteoporosis in Children With Acute Lymphoblastic Leukemia Undergoing Therapy
NCT00330538CI-TRIAL-00000665completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hypothesis: Pediatric patients with acute lymphoblastic leukemia, treated with chronic glucocorticoids as a part of the leukemia treatment protocol, will have an increased incidence and severity of osteoporosis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukemia, Lymphocytic, Acute, L1 | Leukemia | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 4 Years
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All pediatric patients with a new diagnosis of ALL between ages 4-18 * Patients who are expected to receive glucocorticoids as part of the leukemia treatment protocol * Bone density measurements must be performed at the diagnosis visit or maximally within 48 hours after the first dose of glucocorticoids Exclusion Criteria: * Patients under 4 years of age are excluded due to lack of age appropriate standards for bone mineral density * Glucocorticoid therapy of at least one month or longer within the six months prior to DX * History of connective tissue or musculoskeletal disorders * Biphosphonate therapy within the past 6 months * Acute renal failure * Serum creatinine equal to or higher than 4.5mg/dl * Positive serum pregnancy test in adolescent females
References
Publications (0)
Data not yet available
No reference posted for this study.