Clinical trial · Interventional
Lycopene in Preventing Prostate Cancer in Healthy Participants
Mechanism of Prostate Cancer Prevention by Lycopene
NCT00322114CI-TRIAL-00012217unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Chemoprevention is the use of certain drugs or substances to keep cancer from forming, growing, or coming back. The use of lycopene, a substance found in tomatoes, may keep prostate cancer from forming. PURPOSE: This randomized clinical trial is studying how well lycopene works in preventing prostate cancer in healthy participants.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| lycopene | Dietary Supplement | — | UNRESOLVED |
| placebo | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Arm I
- description
- Participants receive an oral tomato dietary supplement containing lycopene twice daily for 3 weeks.
- interventionNames
- Dietary Supplement: lycopene
- type
- EXPERIMENTAL
- label
- Arm II
- description
- Participants receive an oral tomato dietary supplement containing lycopene at a higher dose twice daily for 3 weeks.
- interventionNames
- Dietary Supplement: lycopene
- type
- PLACEBO_COMPARATOR
- label
- Arm III
- description
- Participants receive oral placebo twice daily for 3 weeks.
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Healthy participants * No existing prostate disease PATIENT CHARACTERISTICS: * Able to supply blood and urine samples * Able to answer demographic and dietary recall questionnaires * No hospital inpatients * Not allergic to tomatoes or tomato products * Not abusing alcohol or non-prescribed drugs * No existing gastrointestinal disease or cancer PRIOR CONCURRENT THERAPY: * At least 2 weeks since prior lycopene (in supplement form) * No concurrent participation in another clinical trial
References
Publications (0)
Data not yet available
No reference posted for this study.