Clinical trial · Interventional
Genetic Analysis in Diagnosing Thyroid Cancer in Patients With Thyroid Nodules
Gene Expression Analysis in Thyroid Nodule FNA Samples
NCT00316823CI-TRIAL-00013854completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Finding genetic markers for thyroid cancer in a biopsy specimen may help doctors diagnose thyroid cancer. PURPOSE: This clinical trial is studying how well genetic analysis works in diagnosing thyroid cancer in patients with thyroid nodules.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| diagnostic laboratory biomarker analysis | Other | — | UNRESOLVED |
| gene expression analysis | Genetic | — | UNRESOLVED |
| immunohistochemistry staining method | Other | — | UNRESOLVED |
| needle biopsy | Procedure | — | UNRESOLVED |
| polymerase chain reaction | Genetic | — | UNRESOLVED |
| reverse transcriptase-polymerase chain reaction | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Diagnostic accuracy of biomarkers by mRNA expression analysis
- measure
- Correlate levels of gene expression with the aggressiveness of differentiated thyroid cancer in FNA biopsy samples
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of a thyroid nodule that requires fine-needle aspiration biopsy or thyroidectomy to exclude a diagnosis of thyroid cancer PATIENT CHARACTERISTICS: * Platelet count ≥ 70,000/mm\^3 * PT (INR) ≤ 14.5 * PTT ≤ 35.2 * Not pregnant PRIOR CONCURRENT THERAPY: * No aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) 7 days before sample procurement
References
Publications (0)
Data not yet available
No reference posted for this study.