Clinical trial · Interventional
Pulse Steroids Versus Oral Steroids in Problematic Hemangiomas of Infancy
The Efficacy and Safety of Intravenous Pulse Steroids Compared to Standard Oral Steroids in the Treatment of Problematic Hemangiomas in Infants: A Randomized Controlled Trial
NCT00312520CI-TRIAL-00032582completedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to determine if pulse steroids are more efficacious and safer than the standard treatment with oral corticosteroids.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hemangiomas | Hemangioma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| methylprednisolone | Drug | — | UNRESOLVED |
| prednisolone | Drug | Prednisolone | ALIAS |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Percent improvement in the appearance of hemangioma
Secondary outcomes (2)
- measure
- Frequency of side-effects experienced by the patients
- measure
- Changes in the angiogenesis markers
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Month
- Maximum age
- 4 Months
Show eligibility criteria text
Inclusion Criteria: * problematic facial hemangiomas (periorbital/facial hemangiomas with potential visual obstruction, large/dysfiguring hemangiomas) * 1-4 months of age * signed consent form Exclusion Criteria: * refusal to participate * age \> 4 months * complicated nonvisible hemangiomas * congenital heart disease
References
Publications (0)
Data not yet available
No reference posted for this study.