Clinical trial · Interventional
Clinical Trial of Chemosensitivity Test
Chemosensitivity Test to Evaluate the Effect of Adjuvant Cancer Chemotherapy (S-1) After Gastric Surgery
NCT00287755CI-TRIAL-00005130completedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the usefulness of chemosensitivity test in evaluating the appropriate adjuvant cancer chemotherapy after gastric surgery
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| S-1 | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 1
- interventionNames
- Drug: S-1
Primary outcomes (1)
- measure
- Overall survival rate
- timeFrame
- at three years
Secondary outcomes (1)
- measure
- Side effect
- timeFrame
- During administration of drug
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * histologically proven gastric cancer * PS (ECOG) 0 or 2 * D2 dissection, curability B or more * surgical Stage IIIA and IIIB * negative peritoneal cytology * no previous radiotherapy, chemotherapy and hormone therapy * possible peroral intake at 6 POW * no severe surgical complication * normal bone marrow, liver and renal function * complete chemosensitivity test * written informed consent Exclusion Criteria: * multiple cancer * contraindication for S-1 * history of drug allergy (grade 3) * severe complication * watery diarrhea * pregnant * scirrhous gastric cancer * the other patients who was judged as inadequate for trial by doctor on duty
References
Publications (1)
- DERIVEDTanigawa N, Yamaue H, Ohyama S, Sakuramoto S, Inada T, Kodera Y, Kitagawa Y, Omura K, Terashima M, Sakata Y, Nashimoto A, Yamaguchi T, Chin K, Nomura E, Lee SW, Takeuchi M, Fujii M, Nakajima T. Exploratory phase II trial in a multicenter setting to evaluate the clinical value of a chemosensitivity test in patients with gastric cancer (JACCRO-GC 04, Kubota memorial trial). Gastric Cancer. 2016 Apr;19(2):350-360. doi: 10.1007/s10120-015-0506-z. Epub 2015 Sep 18. PMID 26385385