Clinical trial · Observational
Chromoendoscopy for Ulcerative Colitis Surveillance
Impact of Chromoendoscopy on the Detection of Neoplasia in Ulcerative Colitis
NCT00274209CI-TRIAL-00005797completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Long-standing ulcerative colitis is associated with an increased cancer risk. Chromoendoscopy with dye spraying can detect subtle abnormalities that are not visible with standard endoscopy. The purpose of this study is to determine if chromoendoscopy with fewer "targeted biopsies" can replace standard colonoscopy with multiple "random" biopsies.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Crohn's Disease | — | UNRESOLVED | — |
| Ulcerative Colitis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Chromoendoscopy with magnification | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- IBD patients at risk for neoplasia
- description
- Patients with long-standing ulcerative colitis or Crohn's colitis at risk for neoplasia.
- interventionNames
- Procedure: Chromoendoscopy with magnification
Primary outcomes (1)
- measure
- Prevalence of dysplastic lesions by white light vs. chromoendoscopy
- timeFrame
- 12 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Ulcerative colitis, pancolitis \> 8 years; left-sided \> 15 years or * history of PSC or * history of previous dysplasia on colon biopsies or * family history of colon cancer in first degree relative Exclusion Criteria: * any condition that precludes colonoscopy * expected survival less than 1 year
References
Publications (0)
Data not yet available
No reference posted for this study.