Clinical trial · Observational
Metabolomic Analysis of Lung Cancer
Preoperative Metabolomic Analysis of Primary Lung Cancer: A Translational Clinical Trial of the Brown Cancer Center
NCT00263731CI-TRIAL-00058346completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to learn more about the metabolic properties of lung cancer cells.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Carcinoma, Non-Small Cell Lung | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
| Carcinoma, Small Cell Lung | Lung Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 13-C-glucose | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Group 1 (Experimental Group)
- description
- 250 subjects with suspected or confirmed lung cancer undergoing surgical resection, will receive 13-C-glucose prior to surgery
- interventionNames
- Other: 13-C-glucose
- label
- Group 2 (Control Group)
- description
- 250 subjects with suspected or confirmed lung cancer undergoing surgical resection, will not receive 13-C-glucose prior to surgery
- label
- Group 3 (Healthy Subjects)
- description
- 250 healthy subjects (must be at least 30 years of age and have no prior history of diagnosed lung cancer) will provide 1 blood sample and 1 urine sample.
Primary outcomes (1)
- measure
- metabolic profiles of cancerous vs. healthy lung tissue
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Lung Cancer Patients (Groups 1 \& 2) Inclusion Criteria: * patients with suspected, clinically diagnosed, or histologically diagnosed lung cancer. Occasionally, other cancers (including metastatic cancers to the lung) may be resected for the study as negative controls for NSCLC, as warranted by the particulars of the case. * patients must have general medical conditions to allow them to undergo surgical resection of their primary tumor Exclusion Criteria: * history of diabetes for the experimental group (surgery + glucose); patients with a history of diabetes are allowed in the control group (surgery/no glucose) * known hepatitis C or HIV (AIDS) Healthy Subjects (Group 3) Inclusion Criteria: * at least 30 years of age * preferably be fasting for 12 hours (minimum 8 hours) prior to enrollment Exclusion Criteria: * prior history of diagnosed lung cancer * known hepatitis C or HIV (AIDS)
References
Publications (0)
Data not yet available
No reference posted for this study.