Clinical trial · Interventional
Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy.
The Effectiveness of a Low-Residue Diet on Diarrhea in Cancer Patients Receiving Pelvic Radiation Therapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Eating a diet low in residue (fiber, fat, and certain milk or vegetable products) may help prevent or reduce diarrhea caused by pelvic radiation therapy. PURPOSE: This randomized clinical trial is studying a low-residue diet to see how well it works compared to no dietary intervention in treating diarrhea in patients who are undergoing radiation therapy to the pelvis for uterine, cervical, or prostate cancer.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
| Diarrhea | — | UNRESOLVED | — |
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
| Radiation Toxicity | — | UNRESOLVED | — |
| Sarcoma | Sarcoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| dietary intervention | Dietary Supplement | — | UNRESOLVED |
| management of therapy complications | Procedure | — | UNRESOLVED |
| quality-of-life assessment | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- low-residue diet
- description
- At the onset of diarrhea symptoms, patients are instructed to eat a low-residue diet. Patients continue on this diet for 2-4 weeks.Patients are interviewed weekly for up to six weeks.
- interventionNames
- Dietary Supplement: dietary intervention
- Procedure: management of therapy complications
- Procedure: quality-of-life assessment
- type
- ACTIVE_COMPARATOR
- label
- no dietary intervention
- description
- At the onset of diarrhea symptoms, patients undergo no dietary intervention but are interviewed weekly for up to six weeks.
- interventionNames
- Procedure: management of therapy complications
- Procedure: quality-of-life assessment
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of uterine, cervical, or prostate cancer * Current patient at the Ireland/Case Comprehensive Cancer Center * Planning pelvic radiation therapy within the next 4 months PATIENT CHARACTERISTICS: Performance status * Not specified Life expectancy * Not specified Hematopoietic * Not specified Hepatic * Not specified Renal * Not specified Gastrointestinal * No enteric support * No inflammatory bowel disease Other * No other concurrent illness or medical condition that would preclude study compliance * No history of allergies or dietary intolerances (e.g., lactose intolerance) that would preclude study treatment or interfere with study results PRIOR CONCURRENT THERAPY: Chemotherapy * No concurrent chemotherapy Endocrine therapy * Concurrent hormonal therapy allowed (e.g., testosterone suppression) Radiotherapy * See Disease Characteristics Surgery * No prior colectomy Other * No concurrent glutamine, psyllium, or other fiber supplements (e.g., Benefiber\^® or Metamucil\^®)
References
Publications (0)
Data not yet available