Clinical trial · Interventional
Exercise in Men Receiving Radiation Therapy for Prostate Cancer.
Exercise in Men Receiving Radiation Therapy for Prostate Cancer: Effects on Fatigue, Toxicity, Body Composition, Muscular Fitness, Cardiorespiratory Fitness and Quality of Life.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Androgen Deprivation Therapy is a commonly used treatment for men with Prostate Cancer. Unfortunately this can lead to functional decline, fatigue, increased body fatness, loss of lean body tissue and impaired QOL. Previous research has demonstrated the exercise can may reduce fatigue and improve QOL in men on ADT. This study will evaluate whether aerobic versus resistance exercise over a 24 week period of training will reduce morbidity and improve QOL in men receiving radiation plus or minus ADT with curative intent
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostatic Neoplasms | Prostate Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic cardiovascular exercise program | Behavioral | — | UNRESOLVED |
| Resistance Exercise Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- Control Arm
- description
- No exercise measured
- type
- EXPERIMENTAL
- label
- Aerobic cardiovascular exercise program
- description
- Aerobic cardiovascular exercise program
- interventionNames
- Behavioral: Aerobic cardiovascular exercise program
- type
- EXPERIMENTAL
- label
- Resistance Exercise Program
- description
- Resistance Exercise Program
- interventionNames
- Behavioral: Resistance Exercise Program
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Male
Show eligibility criteria text
Inclusion Criteria: * Prostate Cancer * Radiation Therapy with curative Intent * ADT Exclusion Criteria: * Contraindication to exercise * Uncontrolled hypertension * Uncontrolled Cardiac Disease * Uncontrolled psychotic condition * Unable to obtain informed consent
References
Publications (1)
- RESULTSegal RJ, Reid RD, Courneya KS, Malone SC, Parliament MB, Scott CG, Venner PM, Quinney HA, Jones LW, D'Angelo ME, Wells GA. Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol. 2003 May 1;21(9):1653-9. doi: 10.1200/JCO.2003.09.534. PMID 12721238